According to the latest findings Lavender essential oil "significantly increased social interaction" and has been proposed to be "considered as useful alternative tools to the available traditional treatments for social stress-induced mental illnesses" Silexan (oral lavender oil) preparations are now available on shelf in Australia, along with blends with Zizyphus and Californian poppy and they have comparable effectiveness to SSRIs [1] and benzodiazepines [2] for Generalised Anxiety Disorder in studies and "calming and anxiolytic efficacy" has been proposed for anxiety-related restlessness and disturbed sleep [3] That said, should you be jumping out to buy expensive patented lavender oil? When I was using it orally, I simply measured out Lavandula angustifolia EO and tolerating the terrible flavour... but is diffusing the essential oil just as good a way to go? While the evidence for oral lavender is promising "Research is needed to determine if lavender essential oil aromatherapy, which is readily available worldwide, can be proven to be as effective as Silexan for improving sleep and anxiety in adult patients." [4]. In studies [5], ambient lavender oil might be used as a temporary relief from continued medication for insomnia and showed a trend towards an improved quality of daytime wakefulness and more sustained sleep at night. Inhalation of lavender decreases anxiety and brings the subject to a better mood in 40 healthy adults. Alleviation of anxiety and mood improvement were reported in severely ill patients, who received lavender oil (diluted to 1% concentration) aromatherapy and lavender oil administered in an aroma stream shows modest efficacy in the treatment of agitated behavior in patients with severe dementia A 50:50 blend of Lavender oil and Lemon Balm is promising. Simple inhalation of linalool, a major lavender component altered hypothalamic gene expression in rats under stress and "restored the expression of 560 stress-induced probe sets to a normal status" [6] and has notable effects on the human brain [7] "According to our data, the anxiolytic and antidepressant-like effects attributed to lavender may be due to an antagonism on the NMDA-receptor and inhibition of SERT. This study suggests that lavender essential oil may exert pharmacological properties via modulating the NMDA receptor, the SERT as well" [Review] MoA also includes VDCCs
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